Collagen Induction Therapy (CIT)

What are micro-needling and Collagen Induction Therapy?

Collagen Induction Therapy (CIT) is a minimally-invasive cosmetic procedure that involves the use of a micro-needling device. CIT is safe and effective on all skin types without the risk of discoloration. The micro-needling procedure can be performed by licensed qualified medical professionals including physicians, osteopaths and naturopaths.

CIT is effectively used for:

• Reducing scars caused by acne, surgery or burns
• Fading stretch marks
• Reducing fine lines and deep wrinkles
• Evening skin pigmentation
• Tightening sagging skin

What is the CIT procedure like?

The micro-needling device used looks like a shaving razor with a drum. The drum can differ in widths, and is embedded with up to hundreds of fine micro-needles for penetrating the skin.

The entire procedure is all-natural and fast:

1. The medical professional applies a numbing cream on the treatment area.

2. Then rolls the micro-needling device across the treatment area, puncturing the skin in a specific pattern.

3. As each fine needle punctures the skin, it creates a channel or micro-wound.

4. This creates a controlled injury on and below the skin’s surface. The “injury” triggers the body to “fill” these micro-wounds by producing new collagen and elastin, and by stimulating skin cell regeneration.

5. The patient resumes regular activities almost immediately.

How does CIT work?

CIT or micro-needling works by stimulating the immune system and wound-healing mechanisms. As the micro-needles penetrate the skin causing micro-wounds, it triggers an intense inflammatory reaction that begins a cascade of subsequent reactions.

The important point is: a micro-needling intrusion is caused by tiny surgical needles. The skin's nerve receptors and defense mechanisms sense these fine needle intrusions as a specific type of injury and heals accordingly.

During the healing process, skin cells (within a 1 to 2 mm radius around the pricking channel) release growth signals to undifferentiated cells otherwise known as skin stem cells. These signals also stimulate rapid growth of new fibroblasts and other wound repairing cells.

Many cell types including new fibroblasts rush to close the wound by migrating to the point of intrusion. These new fibroblasts then transform into collagen fibers which integrate with existing collagen in the upper dermis. The new collagen fibers thicken the skin, filling in atrophic scars.

The micro-needling procedure creates thousands of micro wounds in a treatment area. As each wound induces new collagen formation, it forms a new, healthy collagen layer in the treatment area. This reaction is called collagenesis.

The wound healing process also stimulates rapid growth of endothelial cells (the thin layer of cells which line capillaries and blood vessels). In turn, this creates new capillaries for better blood supply to the skin. This reaction is called angiogenesis.

During the micro-needling procedure, tissue damage is unlikely because the needles are very fine and thin. In fact, skin integrity actually remains intact even though the skin reacts as if it had been "injured." The tiny wounds caused by the micro-needles are repaired and close very quickly. No tissue lesion can be detected, infections are rare, and there is nothing to repair.

Before	After
The biopsies above show new collagen and elastin fibers (stained purple) increased 1000% after a Medical Dermaroller® treatment. Histological findings of a blinded study performed in 2006 by Dr. Schwarz and Dr, Laaff from Frieburg, Germany.

See actual results from Medical Dermaroller® procedures:

Before: Severe burn on lower jaw	After: Burn scar reduced by over 60%
Before: Wrinkles in difficult-to-treat areas	After: Wrinkles faded, skin texture and hydration improved, pigmentation evened (3 months after only one treatment)
Before: Severe scarring from acne	After: Skin texture and oil balance improved significantly

SAFETY WARNING

Only professionally designed medical micro-needling devices use sterile, surgical-grade needles. Using anything else puts you at serious risk.

All Medical Dermaroller® micro-needles are specifically designed, tested and patented for optimum Collagen Induction Therapy results. Only Dermaroller® needles contain carefully blended metal alloys to elicit a specific healing response from the body.

IMPORTANT
All Medical Dermaroller® devices are STERILELY PACKAGED, designed for SINGLE USE, AND DISPOSABLE. They are sold only to licensed medical professionals. Medical strength numbing creams should only be applied under medical professional supervision. International patents pending.

CIT WARNING
Collagen Induction Therapy (CIT) is a medical procedure. To avoid complications, disclose your entire medical history, including the use of medications and supplements, to your medical provider prior to undergoing CIT.